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Background: The contribution of various risk factors to the burden of stroke worldwide is unknown, particularly in countries of low and middle income. We aimed to establish the association of known and emerging risk factors with stroke and its primary subtypes, assess the contribution of these risk factors to the burden of stroke, and explore the differences between risk factors for stroke and myocardial infarction. Methods: We undertook a standardised case-control study in 22 countries worldwide between March 1, , and April 23, Cases were patients with acute first stroke within 5 days of symptoms onset and 72 h of hospital admission. Controls had no history of stroke, and were matched with cases for age and sex.
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Lancet: What’s Needed to Protect Health from Climate & COVID | NRDC

Background: The incidence of microcephaly in Brazil in was 20 times higher than in previous years. Congenital microcephaly is associated with genetic factors and several causative agents. Epidemiological data suggest that microcephaly cases in Brazil might be associated with the introduction of Zika virus. We aimed to detect and sequence the Zika virus genome in amniotic fluid samples of two pregnant women in Brazil whose fetuses were diagnosed with microcephaly. The women had presented at 18 weeks' and 10 weeks' gestation, respectively, with clinical manifestations that could have been symptoms of Zika virus infection, including fever, myalgia, and rash.
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Lancet: What’s Needed to Protect Health from Climate & COVID

We have been told repeatedly by health experts to demonstrate the effectiveness of hydroxychloroquine and the other meds prescribed with it we need strict clinical trials. These are studies where some patients receive medication, and some do not. For many healthcare providers, this is a noxious thought if there is evidence to believe a treatment may work. How do you ethically deny a potential treatment to an eligible patient to conduct a study? So-called double-blind studies described above are the preferred method advocated by Dr.
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Background: The degree of protective immunity conferred by infection with severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 is currently unknown. Methods: A year-old man who was a resident of Washoe County in the US state of Nevada presented to health authorities on two occasions with symptoms of viral infection, once at a community testing event in April, , and a second time to primary care then hospital at the end of May and beginning of June, Nasopharyngeal swabs were obtained from the patient at each presentation and twice during follow-up. Sequence data were assessed by two different bioinformatic methodologies.
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